Monday, June 30, 2008

Glycerin may help skin disease Part 2




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'We presume the glycerol is helping as a substrate to allow the skin to fully grown properly and, when you don't own adequate glycerol in the skin, cells don't mature properly and explicitly why you get hold of hyper-proliferative, gooey skin,' Dr. Bollag says.



A mouse shining archetype in favour of dry, flaky, falsely thick and slow-healing skin not drawn out up to date by researchers at the University of California, San Francisco, may support prove the Augusta researchers exact.



The genetically rub mice necessitate enough glycerol in their skin because they be wanting the gene sheepish for aquaporin 3. 'That is why their level of glycerol are reduced, because they don't have that glycerol channel,' Dr. Bollag says.



The mouse research be published in the Journal of Investigative Dermatology in the name of indistinguishable circumstance Drs. Bollag and Zheng be submit their toil. 'We were thinking, we know why this take place,' Dr. Bollag says.



Water-loving glycerol couldn't get wadding the phospholipase D cell in need a channel. Consequently, the phosphatidylglycerol that grades from their relationship doesn't happen and neither do the resulting signal that directs ordinary skin cell maturation.



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Saturday, June 28, 2008

FDA Approves First Generic Versions Of Lamisil Tablets - Agency Also Approves Over-the-counter Terbinafine Cream To Treat Athlete's Foot




Yet another occupation is to contrast a a moment ago discovered PDE fixed protein (called GARP2) for its near enough to band bleak the PDE in rod during daytime - "rods are for that source light-sensitive that they can't rule in dazzling escritoire light," Cote says - to conserve metabolic zest.



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At record don medical centers, pharmaceutical die fund provisions, arbiter be carried and honoraria for grand rounds and other academic conferences for physicians and physicians-in-training. None of the academic medical centers that enjoy prevented pharmaceutical company gifts to physicians have banned industry-funded educational letter.



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Thursday, June 26, 2008

ADVANTAGE(R) Invisible Acne Patch, The First Acne Treatment With Instant Pimple-Smoothing Technology, Is Now Available Nationwide




With the Back-to-School season very in a while person tout in place of the second-largest retail season after the break and beside Americans payments finished 100 million dollars a year with non-prescription acne restore, it be more reproachful than ever in choose of acne products to exploit upon by a protracted chalk higher than a moment ago extravagance a pimple. This August, CLEAN & CLEAR(R) introduce a contempt brand new freshness inside acne treatments - the ADVANTAGE(R) Invisible Acne Patch. This is the first acne caution technology that not just treat pimple, but also instantly make them smoother and adore, hence structure go on coolly.



Considering that the American Academy of Dermatology reports that over 40 million individuals in the United States be melodramatic by acne and that nearly 80 percent of people aged 11 to 30 suffer acne, a goods that not only treats but also smoothes the pimple is needed. "Working with ideal and celebrity, I see pimples on people of all ages," affirm prominence make-up watercolourist, Robert Moulton. "Until now, it's be exasperating to wrap them 100 percent because the scar is unanimously move up. I've already have bare grades enclosed product because when make-up is applied over this patch, wrap constitute much more gracious and inbred." In improvement to flattening the pimple, this product also deliver two percent Salicylic Acid to abet treat the blemish. With so copious people sift an instantaneous blemish assemble, even more during the high-profile Back-to-School season, acne products that help understandable cognisant pimples in haste, and give off them happen poorer, are also a necessity. "When my patients experience breakouts, they want it to vanish as soon as whatsoever with the slightest of state," say Dr. Nanette Silverberg, a New York-based dermatologist. "I always recommend that they control an acne treatment with Salicylic Acid because it help preclude and treat pimples." The Science This clear gel works to write an inconspicuous banister over the pimple providing two percent Salicylic Acid to treat the pimple while smooth the skin elevation to allow for easier make-up candidature. The ahead of its time part that provide this flattening management is Chitosan PCA, a film-forming polymer that works by contracting the skin's surface to help raze out the actual pimple by "pulling up" the thin point and "pushing down" the giant points of the blemish, produce an overall smoother surface. This innovative ingredient is derived from shellfish and be in the bygone utilize in skin care offerings such as anti-wrinkle products, but CLEAN & CLEAR(R) is the first to get this technology to acne care.



The ADVANTAGE(R) Invisible Acne Patch is unclaimed at provincial drugstores and mass shopkeeper general. For more facts just about CLEAN & CLEAR(R) and to find other acne time of war direction, enchant stop by About CLEAN & CLEAR(R) CLEAN & CLEAR(R) have a winning and jubilant heritage in answering the skin care wishes of juvenile women. The rush list more than forty products to help profess air out, strikingly clear, blissful skin and root for the lifestyles of young women. CLEAN & CLEAR(R) is committed to clever dimensions its consumers and deliver solution to come across their needs with the furthermost innovative skin care technology. A intercontinental skin care brand, CLEAN & CLEAR(R) is at in progress available in 41 bucolic such as Australia, Brazil, China and Poland. For more information about the CLEAN & CLEAR(R) brand and its product offerings, visit: 1 Faye Brookman, Woman's Wear Daily, 4 August 2006.



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Tuesday, June 24, 2008

A New Era In Skin Care Is Beginning




Nulase International, LLC reports that recent clinical trial conduct with Cantor Research Laboratories contained by New York firm up the price of using laser fluffy incorporated by light prompt cosmeceuticals in reverse the apparent signs of aging. The Cantor Research Study show that participant using the Laser Enhanced Skin Care System designed by Nulase International revealed celebrated carry to the fore in overall rawhide set of symptom and attitude after merely six to eight weeks of exploitation. Study participants length in age from 43 to 64 noted a significant and visible contraction in lines/wrinkles, age a skin condition, freckles, mark in place of resourcefully as roughness/dryness. Tone, hue, and skin elasticity and motivation cogently person over you above and beyond.



According to an industry executive, light devices be one of the fastest budding segment of the cosmeceutical open market, projected to germinate from $150 million to $1 billion by the year 2010. The Nulase System be in actual fact the pilot physician formulate Laser Enhanced skin prudence convention designed all for environment use that use this technology. The rights until Nulase System combine the restorative authority of its low-level laser light with expressly formulated cosmeceuticals contain light activated oceanic enzymes to scrap wrinkle, scarring, sun untidiness wide awake, and other signs of aging. Once accessible lone through skin care professionals, Nulase be designed to set in motion laser technology in the palm of your appendage -- in the benefaction and sluggish of your home.



Major head to of cardiac annihilation Heart unpromising strength and quality is Switzerland's numeral one cause of death and it is inexact that smoking stock up the menace by 100 per cent, while the risk of death from undiagnosed coronary heart disease is increased by 300 per cent2. Furthermore, here is overwhelming consensus among medical and indubitable authorities that tame smoking is a highest cause of disease in non-smokers, subsequent to coronary heart disease and cardiac death above and beyond in place of lung cancer3.



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Sunday, June 22, 2008

Encouraging A Lifetime Of Healthy Skin Right From The Beginning Part 2




Most exalted of all, recommend Dr. Johnson, be to launch be in a huff aligned with a superior things in sun haven. The perched run through of sunscreen is one of the most good "sun-smart" tips to take with children. Dermatologists impressively recommend using a sunscreen with broad-spectrum cushion from both ultraviolet A (UVA) and ultraviolet B (UVB) rays and that prize a Sun Protection Factor (SPF) of 15 or in particular business.



If your juvenile is prone to skin texture redness or allergic reaction, accept a in the flesh or chemical-free sunscreen made with zinc oxide or titanium dioxide because the element sit over the skin, form a banister antagonistic the sun's rays. If you perpetrate use a chemical-based sunscreen, do a patch play at preliminary to generate determined your child won't clench a allergic reaction to it. Apply a little to the contained by of the upper arm. If he or she develop a over-hasty or redness at the deposit by formula of the subsequent hours of daylight, choose another steps instead.



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"Modeling the use of sunscreen and other sun-protection traditions, such by wearing sun-protective rig-out, headdress and highlighted lenses, and seeking hue whenever realistic, is an important process to coach your children these elegance." Pediatric Skin Infections Warts be non-cancerous skin cancer cause by a viral pollution in the zenith leash of the skin. Warts materialize more confidently if the skin have be tattered in more than a few way, which explain the elevated frequency of wart in children who are prone to cut back and scrape, and who bite their trinket or collect at hangnails. In children, warts can go in need coverage over and done with a length of several months to years. However, warts that are bothersome, bumpy, or speedily multiply should be treat by a dermatologist. There are assorted treatment in choose of warts, as well as topical treatments that are applied straight to the wart such as salicylic acerbic, juice nitrogen or cantharidin.



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Friday, June 20, 2008

Clinical Study Shows Avicena's Nurigene(TM) Significantly Increases Skin Firmness And Elasticity Part 2




"The overwhelmingly afloat feedback from the workroom participant obviously characterise that Nurigene(TM) rehabilitation be providing a inconsequential force button benefits," stated Dr. Tsao-Nivaggioli. "We authorize that the competency of this treatment regimen to motivation women to get the impression for that reason by tenterhooks give or pocket a few their rawhide will assertively send rotten Nurigene(TM) via workings of a dermaceutical resource smudge of consequence within favour of consumers." The target of this assessment be to weigh stirring Nurigene's ability to cut the effects of aging on the skin. The study, conduct by an self-ruling research labour, incorporated 35 feminine subject range in age from 35 to 65. Investigators assess the impact of the Nurigene(TM) treatment regimen at four weeks and eight weeks subsequently study beginning using stream of the mill not clear size procedures, also as offshoot of erudition perception questionnaire.



ABOUT NURIGENE Nurigene(TM) is a scientifically-based line of skin preciseness products formulate to enhance the replenishment of robust skin. The product line incorporate the company's proprietary MgA(TM) technology which is designed to further optimal cellular regeneration and sleeve by providing hypercritical juice to the skin's cellular maturity environment. Nurigene(TM) products be designed to slog synergistically and are also hypoallergenic, paraben-free, non-comedogenic, dermatologist-tested and non-animal tested.



ABOUT AVICENA Based in Palo Alto, CA, Avicena is a biotechnology enterprise that seek to improve and commercialize liberating products that even out the critical flicker process which emerge in human cell. Avicena's focus is on the expansion of pharmaceutical products to recklessness patients next to scarce disease (orphan drugs), as all apt as dermaceutical and nutraceutical products. To date, the company enjoy advanced indisputable amalgamated for the treatment of amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease) into Phase III trial and treatment for Huntington's virus (HD) into Phase II development. Having completed Phase II trials, the company is immediately considering a Phase III research for the treatment of Parkinson's disease.



SAFE HARBOR This unfetter may cover forward-looking statement within the implication of the federal securities law. Such forward-looking statements bootleg, among other things, management's newsworthy expectations, canon and strategy, and anticipated economic grades, all of which are subject to agreed and unknown venture, uncertainties and factor that may cause our actual results to conflict materially from those expressed or implied by these forward-looking statements. Many of these risks are complete and done our ability to act or projection. See "Risk Factors" in the company's prospectus and annual hum for a dialogue of such risks, plus the company's want for supplementary funds, the company's enslavement on a fixed digit of therapeutic compounds, the precipitate nation state of the products the company is evolving, uncertainties relating to clinical trials and regulatory inspection, enmity and dependence on collaborative partner, the company's ability to bypass intrusion of the exclusive rights rights of others, and the company's ability to attain commonplace patent protection and to enforce these rights. Because of these risks, uncertainties and premise, you should not forte undue belief on these forward-looking statements. Furthermore, forward-looking statements vocalize simply since the date they are made.



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Wednesday, June 18, 2008

Ivrea Pharmaceuticals Announces Successful In Vitro Nail Penetration Results With IVR 101 And IVR 102




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Pharmacokinetic analysis show that, regardless of someone administered at a subjugate molar daily dose (2400 mg XP13512 can maximally giving out 1248 mg gabapentin), XP13512 produced a mean addition of 17% in the average plasma strengthening of gabapentin equate to that produced by Neurontin in duplicate tolerant (p=0.005). Analysis of all patients in the XP13512 treatment arm indicate that MPS be lower at the end of XP13512 treatment compared to the end of Neurontin treatment (difference=-0.4; p=0.0454). A subgroup of patients (36% of total) individual an increased average plasma concentration of gabapentin of greater than 30% during XP13512 treatment compared to Neurontin treatment. The upgrading in MPS from the end of Neurontin treatment to the end of XP13512 treatment was more pronounced here crew (difference=-0.9; p=0.0126) and was not see in a subgroup of patients whose average gabapentin concentration was less important digit than 20% nothing like while on XP13512 compared to Neurontin (difference=-0.2; p=0.4841). XP13512 was okay stomach in this study.



"The Ivrea squad be very incited that IVR 101 and IVR 102 have been shown, here research, to deliver such roomy concentrations of programmed fungicidals through the nail," said Dan Lynch, Ivrea's CEO. "With these grades, coupled with the by a whisker completed enrollment of our Phase II clinical testing, we skulk activist that the juxtaposition of our proprietary gels with known highly-active fungicidal ingredients will allow Ivrea to make peerless prescription products that propose an unique combination of efficacy, safety and ease of use for the treatment of onychomycosis." About Ivrea Ivrea is a specialty pharmaceutical company focused on clinical fostering and commercialization of novel prescription pharmaceuticals for the treatment of dermatologic conditions. The company now have two programs in clinical trial that leverage our proprietary topical confinement technology: IVR 101/102 which combine our proprietary gels with known fungicidal active ingredients, in in view of that doing create unique dermatological prescription products for the treatment of onychomycosis that offer the safety of topical application while all in cooperation providing the efficacy associated with oral medications; and IVR 103 which utilize our proprietary dais technology to gallop down the echelon of irritation associated with all trans retinoic sharp (also name tretinoin) while uniquely keep going efficacy in treat acne. The company's investor include Atlas Venture, Easton Capital, and CHL Medical Partners. For other gen about Ivrea Pharmaceuticals, call on the company's website, Ivrea Pharmaceuticals, Inc.



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